Hi please, respond to my peer discussion. 

Hi please, respond to my peer discussion.

Prompt 1: Explain in detail the pathogenesis on how Mr. Fallbrook’s gastroenteritis leads to sepsis and then ARF. 

Gastroenteritis, often known as stomach flu, is the stomach and small intestine inflammation frequently brought on by a parasite, bacterium, or virus (Stuempfig ND, 2022). These three cause inflammation in the small intestine and stomach because they directly infect a person’s GI tract lining. Mr. Fallbrook, who is 66 years old, exhibits the condition’s symptoms in the film, which include nausea, weakness, disorientation, stomach discomfort, fever, and diarrhea. Notably, Mr. Fallbrook has had both hypertension and heart failure. He contracted the bacteria E by eating tainted food, which is what is causing his gastroenteritis. He runs the danger of developing septicemia, a disease that can be fatal if the infection is not treated with antibiotics promptly and effectively. His nurses have begun observing a darkening of his urine, which is explained by this. A poor diet and a history of hypertension both risk developing renal failure.

Prompt 3: Explain the different types of Acute Renal Failure and which type Mr. Fallbrook falls under. 

Acute pre-renal kidney failure is the first of several different forms of kidney failure. Kidney failure is defined by inadequate blood flow. The kidneys are also unable to remove poisons from the blood. The second form is acute intrinsic renal failure brought on by an injury to the kidney directly. Accidents or physical collisions are also potential causes of this trauma. The third kind of kidney failure is chronic pre-renal kidney failure, which develops over time when insufficient blood supply to the kidneys (Schrier et al., 2004). The other form of this ailment is chronic intrinsic kidney failure, which develops when a person’s kidneys have sustained long-term damage due to intrinsic renal disease. Last but not least, there is chronic post-renal kidney failure, a long-term urinary system obstruction that hinders urination. It is evident from the film that Mr. Fallbrook has acute pre-renal kidney failure, which is defined by the kidney’s inability to cause dehydration.

Reference:

Schrier, R. W., Wang, W., Poole, B., & Mitra, A. (2004, July 1). Acute renal failure: Definitions, diagnosis, pathogenesis, and therapy. The Journal of Clinical Investigation. Retrieved September 26, 2022, from https://www.jci.org/articles/view/22353

Stuempfig ND, Seroy J. Viral Gastroenteritis. [Updated 2022 Jun 21]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK518995/